Equine Anti-tetanus Immunoglobulin（F(ab’)2）
Tetanus is a non-communicable disease contracted through exposure to the spores of the bacterium, Clostridium tetani, that exist worldwide in soil and animal intestinal tracts. Tetanus remains a disease with high fatalities, with around 20-50 deaths occurring from every 100 cases.
Equine Anti-tetanus Immunoglobulin（F(ab’)2）, made from tetanus toxoid immunized equine plasma with a high concentration of anti-tetanus antibody, is of the first class quality in the world. It is obtained through the state-in-art production technique, and is widely used in clinics for the prevention and treatment of infections caused by clostridium tetani. The safety in clinical application is greatly improved as a result to high quality standards. It is listed in The state basic medical insurance, employment injury insurance and Birth insurance drug catalogue (Edition 2017) and the State Emergency Drug Index for Online Purchase issued by state health planning commission and covered by these insurances.
Equine Anti-tetanus Immunoglobulin（F(ab’)2）and tetanus antitoxin (TAT) are both produced from horse blood, used for the treatment and prevention of tetanus. However, the production procedure adapted in the production of tetanus antitoxin (TAT) came from 1940s with little improvement. Equine Anti-tetanus Immunoglobulin (F(ab’)2) applies the most advanced technology, with the products containing higher anti-tetanus toxin activity and less impurities than TAT. Subsequently, the Equine Anti-tetanus Immunoglobulin（F(ab’)2）is clinically much safer than the tetanus antitoxin.
The advantages of Equine Anti-tetanus Immunoglobulin（F(ab’)2）
1. F(ab’)2 content has been increased greatly. The purity reaches the highest level among the similar products in the world;
2. Consequentially, the anti-tetanus toxin activity is increased, and impurities are sharply reduced. As a result, the incidence of allergic reaction is reduced to the lowest levels.
Comparison between Equine Anti-tetanus Immunoglobulin（F(ab’)2） and TAT
The Equine Anti-tetanus Immunoglobulin（F(ab’)2）is significantly superior to the standard in “Chinese Pharmacopoeia” Edition 2015 (ChP 2015) on essential quality indices.